Objective. To evaluate the effectiveness of interventional treatment in patients with sustained ventricular tachycardia (VT), as well as to identify predictors of early relapse. Material and methods. The study cohort consisted of 30 patients (18 men and 12 women) aged 60±8 years with documented paroxysm of ventricular tachycardia (VT). The mean follow-up period was 48.4±12.8 weeks. Before hospitalization, all patients underwent a standard set of clinical and instrumental studies (CM, ECHO-CG, MRI with contrast). In patients with the morphology of left ventricular tachycardia, as well as those older than 45 years, selective coronary angiography was performed. Results. The effectiveness of interventional treatment was 83.7%. The relapse group consisted of 5 patients (16.7%). When analyzing the factors influencing the development of relapse, it was found that in the relapse group there was the presence of multi-vessel lesions according to coronary angiography and the presence of fibrous changes in the ventricular myocardium according to MRI. As a result of assessing the probability of developing recurrent VT after RFA depending on the volume of fibrous lesions of the myocardium according to MRI data using ROC analysis. The area under the ROC curve was 0.792 ± 0.127 with 95% CI: 0.542 – 1.000. The resulting model was statistically significant (p = 0.042). The threshold value of the indicator “Percentage of ventricular fibrosis according to MRI” at the cut-off point, which corresponded to the highest value of the Youden index, was 24.7%. The sensitivity and specificity of the model were 80.0% and 96.0%, respectively. When performing a univariate Cox regression analysis, the presence of ischemic origin of VT (OR 10.26; 95% CI 1.140–92.34), VT from the left ventricle (OR 3.39; 95% CI 0.56–20.35) and ventricular fibrosis according to MRI≥24.7% (RR 8.27; 95% CI 1.73–39.43), demonstrated the strongest association with the development of recurrent VT. Taking into account coronary artery (CA) damage (ischemic genesis of tachycardia), as well as its independent effect on the risk of VT recurrence, we conducted a survival analysis using the Kaplan-Meier method. In patients with no coronary artery disease, freedom from VT recurrence after RFA during the observation period was 91.1%, and for the group with ischemic VT – 59.8%. Conclusion. Studying the mechanisms of occurrence and maintenance of VT plays an important role in the development of treatment strategies for patients with this disease. Thanks to the advent of modern nonfluoroscopic navigation mapping, it has become possible to achieve greater efficiency in the treatment of patients with various forms of ventricular arrhythmias.