Purpose – identify indications and evaluate the results of open and minimally invasive endovascular surgical operations in the complex treatment of electrode-induced infective endocarditis (IE). Materials and methods. From 1986 to April 2019, 98 patients with electrode-induced infectious endocarditis were examined and operated on. There were 38 women and 60 men. The average age of the patients was 66.9±16.8 years (from 31 to 81 years). Duke modified criteria were used for the diagnosis of infectious endocarditis, based on clinical, echocardiographic and microbiological data, which were used in close connection with a full-fledged clinical assessment of the patient's condition. The diagnosis "electrode-induced infective endocarditis" included the removal of an infected pace-maker system, surgical and chemical rehabilitation of the intracardiac focus of infection and if it necessary correction of tricuspid heart disease, antibiotic therapy and reimplantation of the new stimulation system. Depending on the method of deimplantation of the electrodes, all patients are divided into 2 groups. Transvenous methods of extraction of endocardial electrodes were applied in 47 patients. Open endocardial electrode removal methods have been used at 51 patients. Of 51 patients, where open methods of deimplantation were used, in 34 (66.7%) cases operations were performed under conditions of artificial blood circulation and in 17 (33.3%) – on a working heart, without using an artificial blood circulation apparatus. Results. 98 patients with electrode-induced infective endocarditis were operated in three clinics of Nizhny Novgorod. Indications for endovascular removal of endocardial electrodes were considered to be infective endocarditis with the presence of vegetation on the intracardiac part of the endocardial electrode less than 1 cm. In the presence of larger vegetation and/or tricuspid valve (ТV) lesions, as well as, if necessary, correction of combined pathology, open operations were performed. All operations on TV were performed only in conditions of cardiopulmonary bypass. Of 34 patients with tricuspid defect correction, reconstructive valvepreserving operations were performed in 22 cases. Conclusion. Despite serious destruction of the intracardiac structures under conditions of active electrodeinduced IE, an adequate correction of various cardiac lesions is possible, which can really improve the results of treatment of this group of severe, in the past, doomed patients. The choice of the volume of the operation with electrode-induced IE depends on the location and extent of the infectious process.